The CASCADE Study is a clinical research study that will look at a potential new treatment for low back pain due to degenerative changes of a spinal disc.

The investigational product is made from a certain type of adult stem cell. It is given as a one-time injection, either alone or in combination with a carrier material. Eligible patients will be randomly assigned (like flipping a coin) to one of three groups: stem cells alone, stem cells mixed with a carrier material, or saline placebo (which looks like the investigational product but contains no active ingredient). There is a 2 out of 3 chance of being assigned to one of the two groups that will receive the stem cells.

Can you help?

We are currently looking for adult patients who are experiencing low back pain due to degenerative changes of a spinal disc to take part in the CASCADE Study.

Your participation in this clinical research study may help to advance our knowledge of the investigational product, and may benefit other people with degenerative changes of a spinal disc in the future.